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CNTF Protéine

Protéine Recombinant CNTF exprimée dans Escherichia coli (E. coli).
N° du produit ABIN7455693

Aperçu rapide pour CNTF Protéine (ABIN7455693)

Antigène

Voir toutes CNTF Protéines
CNTF (Ciliary Neurotrophic Factor (CNTF))

Type de proteíne

Recombinant

Origine

  • 20
  • 10
  • 5
  • 2
  • 2
  • 2
Humain

Source

  • 31
  • 3
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Pureté

Greater than 95 % as determined by reducing SDS-PAGE.
  • Fonction

    Recombinant Human Ciliary Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ala2-Met200 is expressed.

    Attributs du produit

    Extracellular Domain Protein

    Purification

    Affinity purification
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    Produit
    Système d'expression
    Conjugué
    Origin
    Prix à partir de
    Système d'expression HEK-293 Cells
    Conjugué His tag
    Origin Human
    Prix à partir de 12.620,45 €
    Système d'expression Cell-free protein synthesis (CFPS)
    Conjugué Strep Tag
    Origin Human
    Prix à partir de 20.480,57 €

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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, pH 8.0.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Date de péremption

    12 months
  • Antigène

    CNTF (Ciliary Neurotrophic Factor (CNTF))

    Autre désignation

    CNTF

    Sujet

    Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83 % homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.

    Poids moléculaire

    22.93 KDa

    UniProt

    P26441

    Pathways

    Signalistation JAK/STAT
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